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Lynn W Maines Selected Research

olsalazine (Dipentum)

4/2010Efficacy of a novel sphingosine kinase inhibitor in experimental Crohn's disease.
4/2008Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase.

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Lynn W Maines Research Topics

Disease

4Inflammation (Inflammations)
01/2018 - 11/2006
3Neoplasms (Cancer)
01/2018 - 04/2010
2Disease Progression
04/2010 - 04/2008
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
01/2018
1Fatigue
08/2017
1Vomiting
08/2017
1Nausea
08/2017
1Experimental Arthritis
04/2011
1Arthritis (Polyarthritis)
04/2011
1Osteoarthritis
01/2011
1Pain (Aches)
01/2011
1Adenocarcinoma
04/2010
1Crohn Disease (Crohn's Disease)
04/2010
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
04/2008
1Ulcerative Colitis
04/2008
1Diabetic Retinopathy (Retinopathy, Diabetic)
11/2006
1Macular Degeneration (Age-Related Maculopathy)
11/2006
1Epilepsy (Aura)
10/2005
1Schizophrenia (Dementia Praecox)
10/2005

Drug/Important Bio-Agent (IBA)

53- (4- chlorophenyl)- adamantane- 1- carboxylic acid (pyridin-4-ylmethyl)amideIBA
08/2017 - 04/2010
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 11/2006
3Pharmaceutical PreparationsIBA
08/2017 - 10/2005
3sphingosine kinaseIBA
04/2011 - 04/2008
3EnzymesIBA
04/2010 - 04/2008
2Proteins (Proteins, Gene)FDA Link
01/2018 - 11/2006
2SphingosineIBA
08/2017 - 01/2011
2olsalazine (Dipentum)FDA Link
04/2010 - 04/2008
1Glycogen Synthase (Synthase I)IBA
01/2018
1Protein Kinases (Protein Kinase)IBA
01/2018
1Interleukin-6 (Interleukin 6)IBA
01/2018
1CytokinesIBA
01/2018
1Phosphotransferases (Kinase)IBA
08/2017
1LipidsIBA
08/2017
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
08/2017
1Indomethacin (Indometacin)FDA LinkGeneric
04/2011
1SphingolipidsIBA
01/2011
1Dextran SulfateIBA
04/2008
1Retinaldehyde (Retinal)IBA
11/2006
1Streptozocin (Streptozotocin)FDA Link
11/2006
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2006
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
10/2005
1Carrier Proteins (Binding Protein)IBA
10/2005

Therapy/Procedure

2Oral Administration
01/2018 - 04/2010
2Therapeutics
04/2010 - 11/2006